Not sure about how close you setup your next shot, but inside 80 yards, my distance is rarely the distance I can hit a full swing club. If you find a need to fill a distance gap that is difficult to hit with your present setup, then you may need consider different wedges or adjusting the loft. Don’t do it just to get a magic loft separation. Find a need then fill it.

BTW, my setup is a 48F, 54S and 58M. I can adjust to cover a distance. I had a 50F but there was a distance gap between the 50 and the T350 Pw (44 degrees) that resolved better with the 48 (full swings).

Depends. You'll need to either hit them on a trackman, or play a few rounds to see if the gap is manageable. If there is more than 20 yards between them on full swings, then you will need to either bend something to fill that gap better, or add another wedge.